Air: The nearest airport is at Coimbatore , 160-km away from Mudumalai. You can board a direct flight to Coimbatore from Chennai, Kozhikode , Bangalore and Mumbai. Indian Airlines flies Delhi-Kochi via Mumbai and Coimbatore.

All kinds of Regional state transport corporation buses along with private tour / taxi operators travel to Mudumalai from Coimbatore.

Rail: Nearest broad gauge railway head is Mettupalayam (46 kms) from Mudumalai. Major broad-gauge railway junction is Coimbatore . It is connected with all major cities. Mettupalayam to Ooty, is connected by a Mountain Railway which is 4 hours journey.

The sanctuary is located at a distance of 65-km from Udhagamandalam railway station and 95-km from Mysore station. All kinds of Regional state transport corporation buses along with private tour / taxi operators travel to Mudumalai from both the places.

Road: Mudumalai is well connected by good roads. There is a regular bus service from major cities like Bangalore , Mysore , Coimbatore , Calicut , Kanyakumari, Tanjavur, Tirupati , Cochin Kotagiri, Coonoor and Doddabeta. Buses ply regularly to Mudumalai wildlife Sanctuary.

Gudalur (16-km) is the nearest town to the sanctuary, which is situated along the Udhagamandalam - Mysore highway. This sanctuary could be reached from Mysore as well. There are regular buses from Udhagamandalam and Mysore to the Mudumalai sanctuary.